Potent peroxisome proliferator-activated receptor (PPARalpha) activator. Activates also PPARgamma but not PPARdelta. Potent anti-hypercholesterolemic agent. Hypolipidemic compound. Lipogenesis inducer. Tumor promoter. Causes increased cell proliferation and decreased apoptosis. Anti-inflammatory. Inhibits NF-kappaB transcriptional activity and decreases the inflammatory response by reducing the production of inflammatory cytokines (TNF-alpha, IL1beta). Reduces oxidative stress. Increases fatty acid oxidation. Directly affects insulin signaling. Increases glucose uptake. Synonyms: Pirinixic acid, NSC 310038, BRN 0759945, ((4-Chloro-6-((2,3-dimethylphenyl)amino)-2-pyrimidinyl)thio) acetic acid CAS Number: 50892-23-4 Molecular Weight: 323.8 Molecular Formula: C14H14ClN3O2S Solubility: Ethanol, DMSO, dimethyl formamide or PBS (pH 7.2). Appearance: Supplied as an off-white solid. Purity: 98% Storage and Stability: Store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
323.8
Purity:
98%
Form:
Supplied as an off-white solid.
CAS Number:
[50892-23-4]
* VAT and and shipping costs not included. Errors and price changes excepted