JAM1, Recombinant, Human, aa26-238, His-Tag (Junctional Adhesion Molecule A, JAM-A, Junctional Adhesion Molecule 1, JAM-1, Platelet F11 Receptor, PAM-1, Platelet Adhesion Molecule 1, CD321, F11R, JCAM, UNQ264/PRO301)

Product Overview

• Article Name: JAM1, Recombinant, Human, aa26-238, His-Tag (Junctional Adhesion Molecule A, JAM-A, Junctional Adhesion Molecule 1, JAM-1, Platelet F11 Receptor, PAM-1, Platelet Adhesion Molecule 1, CD321, F11R, JCAM, UNQ264/PRO301)
• Biozol Catalog Number: USB-045437
• Supplier Catalog Number: 045437
• Alternative Catalog Number: USB-045437-100,USB-045437-500
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

F11R, also known as CD321, belongs to the immunoglobulin superfamily. It seems to plays a role in epithelial tight junction formation. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. F11R protein can act as a receptor for reovirus, a ligand for the integrin LFA1, involved in leukocyte transmigration, and a platelet receptor. Recombinant protein corresponding to aa26-238 from human F11R, fused to His-tag at N-terminus, expressed in E. coli. Molecular Weight: ~25.8kD (238aa) confirmed by MALDI-TOF Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMLGSVT VHSSEPEVRI PENNPVKLSC AYSGFSSPRV EWKFDQGDTT RLVCYNNKIT ASYEDRVTFL PTGITFKSVT REDTGTYTCM VSEEGGNSYG EVKVKLIVLV PPSKPTVNIP SSATIGNRAV LTCSEQDGSP PSEYTWFKDG IVMPTNPKST RAFSNSSYVL NPTTGELVFD PLSASDTGEY SCEARNGYGT PMTSNAVRME AVERNVGV Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 25.8
• NCBI: 058642
• UniProt: Q9Y624
• Purity: 90% (SDS-PAGE)
• Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 0.15M sodium chloride, 10% glycerol.