NFKBIB, Recombinant, Human, aa1-356, His-Tag (Nuclear Factor kappa B Inhibitor beta, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B Cells Inhibitor beta, NF-kappa-B inhibitor beta, NF-kappa-BIB, I-kappa-B-beta, Ikapp
Biozol Catalog Number:
USB-045446
Supplier Catalog Number:
045446
Alternative Catalog Number:
USB-045446-100,USB-045446-500
Manufacturer:
US Biological
Category:
Molekularbiologie
NFKBIB, also known as NF-kappa-B inhibitor beta, belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Source: Recombinant corresponding to aa1-356 from human NFKBIB, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~40.3kD (380aa) confirmed by MALDI-TOF Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMAGVAC LGKAADADEW CDSGLGSLGP DAAAPGGPGL GAELGPGLSW APLVFGYVTE DGDTALHLAV IHQHEPFLDF LLGFSAGTEY MDLQNDLGQT ALHLAAILGE TSTVEKLYAA GAGLCVAERR GHTALHLACR VGAHACARAL LQPRPRRPRE APDTYLAQGP DRTPDTNHTP VALYPDSDLE KEEEESEEDW KLQLEAENYE GHTPLHVAVI HKDVEMVRLL RDAGADLDKP EPTCGRSPLH LAVEAQAADV LELLLRAGAN PAARMYGGRT PLGSAMLRPN PILARLLRAH GAPEPEGEDE KSGPCSSSSD SDSGDEGDEY DDIVVHSSRS QTRLPPTPAS KPLPDDPRPV Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight:
40.3
Purity:
90% (SDS-PAGE)
Form:
Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 20% glycerol.
* VAT and and shipping costs not included. Errors and price changes excepted
