TIMP-1, Recombinant, Mouse, His-Tag, aa25-205

Product Overview

• Article Name: TIMP-1, Recombinant, Mouse, His-Tag, aa25-205
• Biozol Catalog Number: USB-045987
• Supplier Catalog Number: 045987
• Alternative Catalog Number: USB-045987-20,USB-045987-100
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

TIMP-1, also known as metalloproteinase inhibitor 1, is a member of the TIMP family. Tissue inhibitors of metalloproteinases (TIMP) family are natural inhibitors of the matrix metalloproteinases (MMPs), the zinc enzymes involved in extracellular matrix maintenance and remodeling. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. It has been identified as a multifunctional molecule with divergent functions. Recombinant Mouse TIMP-1, fused to His-Tag at C-terminal, was expressed in insect cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa25-205 from mouse TIMP-1, fused to His-Tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~21kD (187aa) Amino Acid Sequence: CSCAPPHPQT AFCNSDLVIR AKFMGSPEIN ETTLYQRYKI KMTKMLKGFK AVGNAADIRY AYTPVMESLC GYAHKSQNRS EEFLITGRLR NGNLHISACS FLVPWRTLSP AQQRAFSKTY SAGCGVCTVF PCLSIPCKLE SDTHCLWTDQ VLVGSEDYQS RHFACLPRNP GLCTWRSLGA R Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 21
• NCBI: 035723
• UniProt: P12032
• Purity: 95% (SDS-PAGE). Endotoxin: 1EU/1ug (LAL).
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.