IL-18R beta, Recombinant, Human, His-Tag, aa20-356

Product Overview

• Article Name: IL-18R beta, Recombinant, Human, His-Tag, aa20-356
• Biozol Catalog Number: USB-046019
• Supplier Catalog Number: 046019
• Alternative Catalog Number: USB-046019-20,USB-046019-100
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

IL-18 R beta/IL-1 R7, also known as interleukin-18 receptor accessory protein, is a member of the IL-1 family of cytokines that has multiple immunoregulatory functions. It does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. IL18R1 and IL18RAP polymorphisms have been found associated with diseases such as schizophrenia, HSV1 seropositivity and atopic asthma. Recombinant human IL-18 R beta/IL-1 R7 protein, fused to hIgG-His-Tag at C-terminal, was expressed in insect cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa20-356 from human IL-18R beta, fused to hlgG-His-Tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~65.4kD (576aa) Amino Acid Sequence: FNISGCSTKK LLWTYSTRSE EEFVLFCDLP EPQKSHFCHR NRLSPKQVPE HLPFMGSNDL SDVQWYQQPS NGDPLEDIRK SYPHIIQDKC TLHFLTPGVN NSGSYICRPK MIKSPYDVAC CVKMILEVKP QTNASCEYSA SHKQDLLLGS TGSISCPSLS CQSDAQSPAV TWYKNGKLLS VERSNRIVVD EVYDYHQGTY VCDYTQSDTV SSWTVRAVVQ VRTIVGDTKL KPDILDPVED TLEVELGKPL TISCKARFGF ERVFNPVIKW YIKDSDLEWE VSVPEAKSIK STLKDEIIER NIILEKVTQR DLRRKFVCFV QNSIGNTTQS VQLKEKR Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 65.4
• NCBI: 003844
• UniProt: O95256
• Purity: 95% (SDS-PAGE). Endotoxin: 1EU/1ug (LAL).
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.