CD31, Recombinant, Mouse, His-Tag, aa18-590

Product Overview

• Article Name: CD31, Recombinant, Mouse, His-Tag, aa18-590
• Biozol Catalog Number: USB-046037
• Supplier Catalog Number: 046037
• Alternative Catalog Number: USB-046037-20,USB-046037-50,USB-046037-100,USB-046037-250
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

CD31, also known as PECAM-1(platelet endothelial cell adhesion molecule), is a member of the immunoglobulin superfamily. It is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. It plays a role in signalling and is involved in migration of monocytes and neutrophils, natural killer cells, T lymphocytes and CD34+ hematopoietic progenitor cells. Also, it is important for angiogenesis because it enables the formation of new blood vessels through the cell-cell adhesion. It may play a role in a variety of diseases, including cancer, atherosclerosis, and the nervous system diseases. Recombinant mouse CD31/PECAM-1, fused to His-Tag at C-terminal, was expressed in HEK293 cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa18-590 from mouse CD31, fused to His-Tag at C-terminal, expressed in HEK293. Molecular Weight: ~65.3kD (579aa) Amino Acid Sequence: EENSFTINSI HMESLPSWEV MNGQQLTLEC LVDISTTSKS RSQHRVLFYK DDAMVYNVTS REHTESYVIP QARVFHSGKY KCTVMLNNKE KTTIEYEVKV HGVSKPKVTL DKKEVTEGGV VTVNCSLQEE KPPIFFKIEK LEVGTKFVKR RIDKTSNENF VLMEFPIEAQ DHVLVFRCQA GILSGFKLQE SEPIRSEYVT VQESFSTPKF EIKPPGMIIE GDQLHIRCIV QVTHLVQEFT EIIIQKDKAI VATSKQSSEA VYSVMAMVEY SGHYTCKVES NRISKASSIM VNITELFPKP KLEFSSSRLD QGELLDLSCS VSGTPVANFT IQKEETVLSQ YQNFSKIAEE SDSGEYSCTA GIGKVVKRSG LVPIQVCEML SKPSIFHDAK SEIIKGHAIG ISCQSENGTA PITYHLMKAK SDFQTLEVTS NDPATFTDKP TRDMEYQCRA DNCHSHPAVF SEILRVRVIA PVDEVVISIL SSNEVQSGSE MVLRCSVKEG TSPITFQFYK EKEDRPFHQA VVNDTQAFWH NKQASKKQEG QYYCTASNRA SSMRTSPRSS TLAVRVFLAP WKK Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 65.3
• NCBI: 032842
• UniProt: Q08481
• Purity: 95% (SDS-PAGE). Endotoxin: 1EU/1ug (LAL).
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.