CD16a, Recombinant, Human, His-Tag, aa18-208

Product Overview

• Article Name: CD16a, Recombinant, Human, His-Tag, aa18-208
• Biozol Catalog Number: USB-046047
• Supplier Catalog Number: 046047
• Alternative Catalog Number: USB-046047-20,USB-046047-100
• Manufacturer: US Biological
• Category: Molekularbiologie

Product Description

FCGR3A, also known as low affinity immunoglobulin gamma Fc region receptor III-A, is a multifunctional, low or intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is expressed on human NK cells as an integral membrane glycoprotein anchored through a transmembrane peptide. It mediates antibody dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Recombinant human FCGR3A, fused to His-Tag at C-terminal, was expressed in insect cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa18-208 from human CD16a, fused to His-Tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~22.8kD (200aa) Amino Acid Sequence: MRTEDLP KAVVFLEPQW YRVLEKDSVT LKCQGAYSPE DNSTQWFHNE SLISSQASSY FIDAATVDDS GEYRCQTNLS TLSDPVQLEV HIGWLLLQAP RWVFKEEDPI HLRCHSWKNT ALHKVTYLQN GKGRKYFHHN SDFYIPKATL KDSGSYFCRG LFGSKNVSSE TVNITITQGL AVSTISSFFP PGYQ Biological Activity: Measured by its binding ability in a functional ELISA with Human IgG1 Fc. Applications: Suitable for use in SDS-PAGE, Bioactivity. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 22.8
• NCBI: 001121065
• UniProt: P08637
• Purity: 95% (SDS-PAGE). Endotoxin: 1EU/1ug (LAL).
• Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.