EX-527, SIRT1 Inhibitor (6-Chloro-2,3,4,9-tetrahydro-1Hcarbazole- 1-carboxamide (racemic)), CAS [[49843-98-3]]
Biozol Catalog Number:
USB-136777
Supplier Catalog Number:
136777
Alternative Catalog Number:
USB-136777-5,USB-136777-25
Manufacturer:
US Biological
Category:
Biochemikalien
Selective SIRT1 inhibitor (IC50=98nM). Does not inhibit other HDACs or SIRT family members. Increases p53 acetylation following DNA damage. Cell permeable. Solubility: DMSO (~18mg/ml) or Ethanol (~10mg/ml) Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight:
248.7
Purity:
~98% (TLC)
Form:
Supplied as a lyophilized powder in PBS. Reconstitute with sterile dH20.
CAS Number:
[49843-98-3]
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