PPP1A (Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, protein phosphatase 1, catalytic subunit, alpha isoform, serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit, Protein Phosphatase 1 alpha, PPP
Biozol Catalog Number:
USB-143231
Supplier Catalog Number:
143231
Alternative Catalog Number:
USB-143231-100
Manufacturer:
US Biological
Host:
Mouse
Category:
Antikörper
Application:
IHC, WB
Immunogen:
Purified recombinant human PPP1CA protein fragments expressed in E. coli.
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Applications: Suitable for use in Western Blot and Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Immunocytochemistry: 300 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clonality:
Monoclonal
Clone Designation:
[13k104]
Isotype:
IgG1
Purity:
Purified by immunoaffinity chromatography.
Form:
Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM NaCl, 0.2% sodium azide, 50% glycerol.
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