CA 074 (N-[[(2S,3S)-3-[(Propylamino)carbony l]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline), CAS [[134448-10-5]]

Product Overview

• Article Name: CA 074 (N-[[(2S,3S)-3-[(Propylamino)carbony l]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline), CAS [[134448-10-5]]
• Biozol Catalog Number: USB-145664
• Supplier Catalog Number: 145664
• Alternative Catalog Number: USB-145664-1
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Inhibitor of cathepsin B (Ki = 2-5nm). Displays selectivity over cathepsins H and L (Ki = 40-200um). Shown to reduce bone metastasis in a 4T1.2 breast cancer model. Sequence: C18H29N3O6 Solubility: DMSO (~20mM), Ethanol (~20mM) Molecular Weight: ~383.44 Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 383.44
• Purity: ~98% (HPLC)
• Form: Supplied as a white lyophilized solid.
• CAS Number: [134448-10-5]