S-Duloxetine Hydrochloride (Potent 5-HT and NA Reuptake Inhibitor, Blocks Dopamine Reuptake, (+)-S-N-Methyl-3-(1-naphthyloxy)- 3-(2-thienyl)propanamine hydrochloride), CAS [[136434-34-9]]

Product Overview

• Article Name: S-Duloxetine Hydrochloride (Potent 5-HT and NA Reuptake Inhibitor, Blocks Dopamine Reuptake, (+)-S-N-Methyl-3-(1-naphthyloxy)- 3-(2-thienyl)propanamine hydrochloride), CAS [[136434-34-9]]
• Biozol Catalog Number: USB-145691
• Supplier Catalog Number: 145691
• Alternative Catalog Number: USB-145691-10,USB-145691-50
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

High affinity, competitive 5-HT and norepinephrine (NE) re-uptake inhibitor (Ki values are 8.5 and 45nm for 5-HT and NE reuptake respectively in cortical synaptosomes, IC50 values are 28 and 46nm for 5-HT and NE reuptake respectively in rat hippocampal slices). Also blocks dopamine reuptake (Ki=300nm in striatal synaptosomes). Exhibits antidepressant and anxiolytic effects. Orally bioavailable. CAS Number: 136434-34-9 Formula: C18H19NOS.HCl Solubility: DMSO (~100mM), H2O (~10mM) with gentle warming Molecular Weight: ~333.88 Storage and Stability: Store at RT. Stable for 12 months.

Product Properties

• Molecular Weight: 333.88
• Purity: 99% (HPLC)
• Form: Supplied as a off-white solid.
• CAS Number: [136434-34-9]