Arimoclomol is a orally administered drug used to treat amyotrophic lateral sclerosis and was later discovered to be a potential insulin resistance treatment and diabetic complications. Arimoclomol is believed to function by stimulating a normal cellular protein repair pathway through the activation of molecular chaperones. Arimoclomol could treat a broad range of diseases. Arimoclomol activates the heat shock response. It is believed to act at Hsp70. Melting Point: >131C (dec.) Solubility: DMSO (Slightly), Methanol (Slightly) Atmosphere: Inert Gas Method for Determining Identity: Proton NMR (DMSO-d6) Spectroscopic and Mass Spectrometric Analysis TLC Conditions: C18, Acetonitrile: Water: Ammonium Hydroxide=6:4:0.1, Visualized with UV and KMnO4, Single Spot, Rf=0.25 Specific Rotation: +2.5 (c=0.4, Methanol) Elemental Analysis: Calculated: %C: 50.29, %H: 5.63, %N: 9.78 Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Light sensitive.
Molecular Weight:
429.85
Purity:
~95%
Form:
Supplied as an off-white to pale beige solid
CAS Number:
[289893-26-1]
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