Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Synonyms: (alphaS)-alpha-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide, (alphaS)-alpha-[(4-Morpholinylacetyl)amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-phenylalaninamide, PR 171 CAS No: 868540-17-4 Molecular Formula: C40H57N5O7 Molecular Weight: 719.91 Purity: 98% (HPLC and TLC) Appearance: White to off-white solid Solubility: Soluble in DMSO and DMF at 15mg/ml, soluble in ethanol at 1mg/ml with warming, slightly soluble in water. Melting Point: 204-210C (lit) Method of Determining Identity: Proton NMR Spectroscopic and Mass Spectrometric Analysis Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. Stable for 6 months after receipt.. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
719.91
CAS Number:
[868540-17-4]
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