DL-Methotrexate Dipotassium Salt Dihydrate, CAS [[Free acid: 60388-53-6]]

Product Overview

• Article Name: DL-Methotrexate Dipotassium Salt Dihydrate, CAS [[Free acid: 60388-53-6]]
• Biozol Catalog Number: USB-163934
• Supplier Catalog Number: 163934
• Alternative Catalog Number: USB-163934-25
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

DL-Methotrexate is a folic acid antagonist and potent anticancer agent. Amethopterin blocks DNA synthesis by preventing the production of tetrahydrofolate cofactors which are required to make thymidine. Amethopterin is actively transported into cells by the folate transporter where it is converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, a dihydrofolate reductase inhibitor. Synonyms: N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-glutamic Acid Dipotassium Salt Dihydrate, DL-AmethopterinvDipotassium Salt Dihydrate, NSC 117356 Dipotassium Salt Dihydrate CAS No: Free acid: 60388-53-6 Molecular Formula: C20H24K2N8O7 Molecular Weight: 566.65 Appearance: Yellow to light orange powder Purity: As reported Melting Point: xxxC Solubility: Add a minimal amount of 0.1N NaOH to solubilize, then dilute in neutral buffer or saline. Diluted stock is stable for 1 week refrigerated and for 1 month frozen at -20 C Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 566.65
• Purity: As reported
• Form: Yellow to light orange powder
• CAS Number: [Free acid: 60388-53-6]