Tetrahydrocortisol is excreted in large amounts in premenopausal patients with early breast cancer. Tetrahydrocortisol has been found to be produced by lymphocytes in both normal and cancer bearing patients however, the concentration of Tetrahydrocortisol has increased in patients with cancer. Melting Point: 200-203C Solubility: Chloroform (sparingly), Methanol Method for Determining Identity: Proton (CDCl3) NMR Spectroscopic and Mass Spectrometric Analysis TLC Conditions: SiO2, Dichloromethane: Methanol=9:1, Visualized with KMnO4, (Single spot, Rf=0.35) Elemental Analysis: Calculated: %C: 68.82, %H: 9.35 Specific Rotation: +86.1 (c=0.31, Methanol) Storage and Stability: Store at -20C under an atmosphere of inert gas. Stable for 6 months after receipt. Caution: Hygroscopic. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
366.49
Purity:
95%
Form:
Supplied as a white to off-white solid
CAS Number:
[53-02-1]
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