Paprotrain ((Z) a-(3-Pyridinylmethylene)-1H-indo le-3-acetonitrile), CAS [[57046-73-8]]

Product Overview

• Article Name: Paprotrain ((Z) a-(3-Pyridinylmethylene)-1H-indo le-3-acetonitrile), CAS [[57046-73-8]]
• Biozol Catalog Number: USB-167689
• Supplier Catalog Number: 167689
• Alternative Catalog Number: USB-167689-10,USB-167689-50
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Solubility: 100mM in DMSO and 10mM in ethanol Molecular Weight: ~245.28 Biological Activity: Reversible, non-ATP competitive inhibitor of mitotic kinesin-like protein 2 (MKLP-2) (Ki = 3.4um). Inhibits the basal ATPase activity of MKLP-2 (IC50 = 1.35um). Exhibits selectivity for MKLP-2 over 12 other members of the kinesin superfamily, including the closely-related MKLP-1. Cell permeable. Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 245.28
• Purity: ~99%
• Form: Supplied as a yellow solid.
• CAS Number: [57046-73-8]