Endothelin B Receptor (EDNRB, ABCDS, Endothelin B Receptor, Etb Receptor, ET-B, Et-b Receptor, Et-b-r, ET-RB, ETBR, ETRB, Etb-svr, WS4A, Endothelin Receptor Type B, ET-BR, ETB, HSCR, HSCR2), Rabbit
Biozol Catalog Number:
USB-170440
Supplier Catalog Number:
170440
Alternative Catalog Number:
USB-170440-50
Manufacturer:
US Biological
Host:
Rabbit
Category:
Antikörper
Application:
IHC, WB
Immunogen:
Synthetic peptide corresponding to 19aa from the N-terminus of human EDNRB. Species sequence homology: gorilla and gibbon.
The Endothelin Receptor ETB is expressed in most tissues. Mutations of the receptor gene are responsible for Hirschsprung disease type 2, a multigenic disorder with phenotypes such as bicolored irides, megacolon, hypopigmentation, and hearing loss. The ETB receptor has similar affinity for all three endothelins and activates a phosphatidylinositol-calcium second messenger system. Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 4-11ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
