Potent, less toxic analog of geldanamycin. Inhibits the essential ATPase activity of HSP90. Telomerase activity inhibitor. Apoptosis inducer and antitumor compound. Synonyms: 17-(Allylamino)-17-desmethoxygeldanamycin, KOS 953, NSC 330507, Tanespimycin, CP 127374, BMS 722782 CAS Number: 75747-14-7 Source: Semi-synthetic derivative from geldanamycin Formula: C31H43N3O8 Solubility: DMSO (~10mg/ml) or methanol (~10mg/ml) Molecular Weight: 585.7 Melting Point: >194C (dec.) Appearance: Supplied as a red to dark red powder. Purity: 98% (HPLC) Storage and Stability: May be stored at 4C for short-term only. Long-term storage is recommended at -20C. Stable for 1 year after receipt. Protect from light when in solution. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Molecular Weight:
585.7
Purity:
98% (HPLC)
Form:
Supplied as a red to dark red powder.
CAS Number:
[75747-14-7]
* VAT and and shipping costs not included. Errors and price changes excepted
