Mycotoxin. Antifungal. Phytotoxic. Shown to possess DNA strand-breaking activity. Inhibits the activity of topoisomerase IIalpha (Topo IIalpha) in mammalian cells. Synonyms: 9-O-Methylalternariol, Djalonensone, AME, BRN 0253553, 3,7-Dihydroxy-9-methoxy-1-methyl-6H-benzo[c]chromen-6-one CAS Number: 26894-49-5 Source: Alternaria sp. Formula: C15H12O5 Method for Determining Identity: Proton NMR Solubility: Methanol, dichloromethane or methylene chloride Molecular Weight: ~272.3 Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight:
272.3
Purity:
98% (HPLC)
Form:
Supplied as an off-white to light brown solid.
CAS Number:
[26894-49-5]
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