Concanamycin B (High Purity) (8-Deethyl-8-methylconcanamycin A), CAS [[81552-33-2]]

Product Overview

• Article Name: Concanamycin B (High Purity) (8-Deethyl-8-methylconcanamycin A), CAS [[81552-33-2]]
• Biozol Catalog Number: USB-207133
• Supplier Catalog Number: 207133
• Alternative Catalog Number: USB-207133-25,USB-207133-100,USB-207133-500
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Antibiotic. Exhibits similar activity as concanamycin A and concanamycin C. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Suppresses bone resorption. Inhibits proliferation of mouse splenic lymphocytes. Antifungal and larvicidal. CAS Number: 81552-33-2 Source: Streptomyces sp. Formula: C45H73NO14 Solubility: DMSO, chloroform, acetonitrile or methanol, insoluble in H2O. Molecular Weight: 852.1 Method for Determining Identity: Proton NMR Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 852.1
• Purity: 98% (HPLC)
• Form: Supplied as a white to off-white solid.
• CAS Number: [81552-33-2]