Antifungal. Cytotoxic against some tumor cell lines, partly attributed to inhibition of Ras-inducible genes. Inhibits proliferation of mouse and human T cells. Modulates production of cytokines during T cell activation. Facilitates the ubiquitinylation process of cyclin D1. Potent and selective threonine/tyrosine-specific kinase, MEK and other protein kinases inhibitor in both in vitro and in vivo studies. Synonyms: 3H-Oxireno[k][2]benzoxacyclotetradecin-5,11(2H,4H)-dione,1a,8,9,15b-tetrahydro-3,4,12-trihydroxy-14-methoxy-9-methyl-,(1aR,3S,4S,6Z,9S,15bR)-, NSC354462 CAS Number: 76958-67-3 Source: Phoma sp. Molecular Formula: C19H22O8 Solubility: Soluble in DMSO or acetone, insoluble in methanol or H2O. Molecular Weight: 378.4 Method for Determining Identity: Proton NMR Purity: 98% (HPLC) Appearance: Supplied as a white to off-white solid. Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
378.4
Purity:
98% (HPLC)
Form:
Supplied as a white to off-white solid.
CAS Number:
[76958-67-3]
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