Peptide antibiotic. Antibcaterial. Plant growth stimulator. Induces root curvature and malformation in plants. Mycotoxin. Prevents interleukin-1 (IL-1) induced endothelial changes by inhibition of protein synthesis. Inhibitor of interleukin-1 beta (IL1 beta) binding to its receptor. Enhancer of cellular fibrinolytic activity. Disrupts the cell cycle at the G2 checkpoint of cancer cells, leading to sensitization of the cancer cells to anti-cancer reagents. Anticancer compound. Cytotoxic against several cancer cell lines. Antimalarial and antitrypanosomal. Inhibitor of BRAF-mutated melanoma cell lines. Synonyms: Malformin A, Cyclic(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-isoleucyl)cyclic(1-2)-disulfide, cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-isoleucyl), cyclic (12)-disulfide Source: Synthetic. Originally isolated from Aspergillus niger. CAS No: 3022-92-2 Molecular Weight: 529.7 Molecular Formula: C23H39N5O5S2 Solubility: DMSO Purity: 95% (HPLC) Appearance: White solid. Storage and Stability: May be stored at 4C for short-term only. Long-term storage is recommended at -20C. Stable for 1 year after receipt. Protect from light when in solution. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
529.7
Purity:
95% (HPLC)
Form:
Supplied as a white solid.
CAS Number:
[3022-92-2]
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