| Wide range of tyrosine and serine/threonine protein kinase inhibitor, including Syk, p56lck, PKA, PKC, MLCK, CDPK, JNK and PI3K. Inhibits the tyrosine phosphorylation of STAT3 and STAT5. Potent apoptosis inducer. Potent anticancer compound. Suppresses NF-kB activation through IkBalpha kinase inhibition. Activator of human deacetylase SIRT1 (sirtuin 1). Potent antioxidant with anti-proliferative, anti-inflammatory and cardioprotective properties. Neuoprotective. Adipogenesis inhibitor. Promotes glucose uptake, AMPK phosphorylation and GLUT4 translocation. Alternate Names: (E)-4-[2-(3,5Dihydroxyphenyl)ethenyl]1,2-benzenediol, 3,3',4,5'-Stilbenetetrol, 3,3',4,5'-Tetrahydroxy-trans-stilbene, Astringenin CAS Number: 10083-24-6 Source: Synthetic. Originally isolated from Euphorbia lagascae. Molecular Formula: C14H12O4 Solubility: Soluble in DMSO, dimethyl formamide, ethanol, methanol, acetone or ethyl acetate. Slightly soluble in H2O. Molecular Weight: 244.3 Purity: 98% (HPLC) Appearance: Supplied as an off-white to light pink crystalline solid. Storage and Stability: Store at 4C. Protect from light and moisture. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures. |
