Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines. CAS Number: 918505-84-7 Source: Synthetic Alternate Names: N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide, Propane-1-sulfonic acid-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluoro-phenyl)-amide, Raf Kinase Inhibitor V Molecular Formula: C17H14ClF2N3O3S Solubility: DMSO or ethanol Molecular Weight: 413.8 Purity: 99% (HPLC) Appearance: Supplied as an off-white solid. Storage and Stability: May be stored at 4C for short-term only. Long-term storage is recommended at -20C. Stable for 1 year after receipt. Protect from light when in solution. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Molecular Weight:
413.8
Purity:
99% (HPLC)
Form:
Supplied as an off-white solid.
CAS Number:
[918505-84-7]
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