Potent and selective inhibitor of cyclin dependent kinases CDK1, CDK2, CDK5 and CDK9. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Casein kinase 1 (CK1delta/epsilon) inhibitor. Potential anti-inflammatory compound. Potential antidiabetic compound. CAS No: 1133437-80-5 Molecular Formula: C25H30N6O Molecular Weight: 430.6 Solubility: DMSO or ethanol. Stock solutions can be made up to 10mM in DMSO. Method for Determining Identity: Proton NMR Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with DMSO or ethanol. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight:
430.6
Purity:
95% (NMR)
Form:
Supplied as a white to off-white solid.
CAS Number:
[1133437-80-5]
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