Rebeccamycin (NSC 359079, BRN 4732638), CAS [[93908-02-2]]

Product Overview

• Article Name: Rebeccamycin (NSC 359079, BRN 4732638), CAS [[93908-02-2]]
• Biozol Catalog Number: USB-207378
• Supplier Catalog Number: 207378
• Alternative Catalog Number: USB-207378-250,USB-207378-1
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Antibiotic. Weak topoisomerase I (Topo I) inhibitor. Structurally similar to staurosporine. Does not show any inhibitory activity against protein kinases. Shows significant antitumor properties in vitro (IC50=480nM against mouse B16 melanoma cells and IC50 =500nM against P388 leukemia cells). Does not show any inhibitory activity against protein kinases. Synonyms: NSC 359079, BRN 4732638, 1,11-dichloro-12,13-dihydro-12-(4-O-methyl-beta-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione CAS Mo: 93908-02-2 Source: Streptomyces sp. Molecular Formula: C27H21Cl2N3O7 Molecular Weight: 570.4 Solubility: DMSO Method for Determining Identity: Proton NMR Purity: 98% (HPLC) Appearance: Supplied as a yellow solid. Storage and Stability: May be stored at 4C for short-term only. Long-term storage is recommended at -20C. Stable for 1 year after receipt. Protect from light when in solution. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 570.4
• Purity: 98% (HPLC)
• Form: Supplied as a yellow solid.
• CAS Number: [93908-02-2]