Resiquimod (R-848, S 28463), CAS [[144875-48-9]]

Product Overview

• Article Name: Resiquimod (R-848, S 28463), CAS [[144875-48-9]]
• Biozol Catalog Number: USB-207380
• Supplier Catalog Number: 207380
• Alternative Catalog Number: USB-207380-5,USB-207380-10,USB-207380-25,USB-207380-50,USB-207380-100
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Immune response modifier. Potent antitumor and antiviral compound. Stimulates antibody secretion and cytokine production. Used as adjuvant to increase the effectiveness of vaccines. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway and leads to the induction of NF-kappaB. NLRP3/NALP3 inflammasome activator, independent of TLRs and RIG-I. Upregulator of the opioid growth factor receptor. Used in the treatment of skin lesions such as herpes simplex virus. Synonyms: 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol, 4-Amino-2-(ethoxymethyl)-1-(2-hydroxyisobutyl)imidazo[4,5-c]quinoline, 4-Amino-2-ethoxymethyl-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol, R 848, Resiquimod, S 28463 CAS Number: 144875-48-9 Molecular Formula: C17H22N4O2 Molecular Weight: 314.4 Appearance: White to off-white powder Purity: 98% Solubility: Soluble in DMSO, dichloromethane or methanol. Slightly soluble in acetonitrile or ethyl acetate. Storage and Stability: Store at -20C.. Stable for 12 months after receipt. Light sensitive.

Product Properties

• Molecular Weight: 314.4
• Purity: 98% (HPLC)
• Form: White to off-white powder
• CAS Number: [144875-48-9]