Tripolin A ((3E)-3-[(2,5-Dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one), CAS [[1148118-92-6]]

Product Overview

• Article Name: Tripolin A ((3E)-3-[(2,5-Dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one), CAS [[1148118-92-6]]
• Biozol Catalog Number: USB-207427
• Supplier Catalog Number: 207427
• Alternative Catalog Number: USB-207427-1,USB-207427-5
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Specific non-ATP competitive Aurora A kinase inhibitor. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase. Sequence: [(3E)-3-[(2,5-Dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one] Solubility: DMSO (10mg/ml) Molecular Weight: ~253.3 Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 253.3
• Purity: 98% (HPLC, NMR)
• Form: Supplied as a yellow solid.
• CAS Number: [1148118-92-6]