ADAM10 (ADAM-10 A Disintegrin and Metalloproteinase Domain 10), IgG2, Clone: [14L14], Rat, Monoclonal
Biozol Catalog Number:
USB-216110
Supplier Catalog Number:
216110
Alternative Catalog Number:
USB-216110-50
Manufacturer:
US Biological
Host:
Rat
Category:
Antikörper
Application:
FC, WB
Immunogen:
Recombinant protein corresponding to mouse ADAM-10.
Members of the ADAM or MDC (Metalloprotease, Disintegrin, Cysteine-rich) family contain pro, metalloprotease-like, disintegrin-like, cysteine-rich, transmembrane and cytoplasmic domains. They play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. Over 30 members have been identified and about half of them are active metalloproteases such as ADAM8, 9, 10, 12 and 17/TACE. Applications: Suitable for use in Flow Cytometry and Western Blot. Other applications not tested. Recommended Dilution: Immunofluorescence: 1:500-1:1000 Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clonality:
Monoclonal
Clone Designation:
[14L14]
Isotype:
IgG2
Purity:
Purified by Protein G affinity chromatography from culture supernatant.
Form:
Supplied as a lyophilized powder in PBS. Reconstitute with 200ul sterile PBS.
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