Bupropion Hydrochloride (Dopamine and Noradrenalin Transporter Inibitor, Bupropion), CAS [[31677-93-7]]
Biozol Catalog Number:
USB-217232
Supplier Catalog Number:
217232
Alternative Catalog Number:
USB-217232-50
Manufacturer:
US Biological
Category:
Biochemikalien
A non-selective inhibitor of dopamine and noradrenalin transporters (Ki = 1.4, 2.8 and 45uM for dopamine, noradrenalin, and serotonin transporters respectively). Also an antagonist for neuronal nicotinic acetylcholine receptors (nAChrs) (IC50 = 1.8uM at alpha2beta2 receptor). Clinically used as an antidepressant and smoking cessation drug. Used in nicotinic addiction and depression studies. CAS Number: 31677-93-7 Molecular Formula: C13H18ClNOHCl Solubility: H2O Primary Target: DAT/NET Primary Target Ki: 1.4u Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Purity:
99% (HPLC)
Form:
Supplied as a white solid.
CAS Number:
[31677-93-7]
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