Casein Kinase I Inhibitor III, PF-4800567, CAS [[1188296-52-7]]

Product Overview

• Article Name: Casein Kinase I Inhibitor III, PF-4800567, CAS [[1188296-52-7]]
• Biozol Catalog Number: USB-217250
• Supplier Catalog Number: 217250
• Alternative Catalog Number: USB-217250-5,USB-217250-10
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

PF-4800567 is a selective inhibitor of casein kinase 1epsilon (CK1epsilon, IC50 = 32 nM) with greater than 20-fold selectivity over CK1delta. It blocks CK1epsilon-mediated PER3 nuclear localization and PER2 degradation, both of which are proteins important for maintaining circadian rhythms in cells. PF-4800567 has been used in the study of the CK1 enzymes in the regulation of circadian rhythm and is also reported to have neuroprotective effects. Synonyms: 3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAS No: 1188296-52-7 Molecular Formula: C17H18ClN5O2 Molecular Weight: 359.8 Purity: 99% Appearance: Crystalline solid Storage and Stability: Storage at -20C under inert gas. Light sensitive.

Product Properties

• Molecular Weight: 359.8
• CAS Number: [1188296-52-7]