CB2 Inverse Agonist, SR 144528 (5- (4- chloro- 3- methylphenyl)- 1- [(4- methylphenyl)methyl]- N- [(1S, 2S, 4R)- 1, 3, 3- trimethylbicyclo[2.2.1]hept- 2- yl]- 1H- pyrazole-3), CAS [[192703-06-3]]

Product Overview

• Article Name: CB2 Inverse Agonist, SR 144528 (5- (4- chloro- 3- methylphenyl)- 1- [(4- methylphenyl)methyl]- N- [(1S, 2S, 4R)- 1, 3, 3- trimethylbicyclo[2.2.1]hept- 2- yl]- 1H- pyrazole-3), CAS [[192703-06-3]]
• Biozol Catalog Number: USB-217257
• Supplier Catalog Number: 217257
• Alternative Catalog Number: USB-217257-5
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A selective inverse agonist for peripheral cannabinoid (CB2) receptors (Ki = 0.6nM and 400nM for CB2 and CB1 receptors, respectively). Has been used in studies related to control of pain initiation, suppression of inflammation, and immune activation. CAS Number: 192703-06-3 Formula: C29H34ClN3O Solubility: DMSO Primary Target: CB2 Receptor Primary Target Ki: 0.6nM and 400nM for CB2 and CB1 receptors, respectively. Molar Mass: 475.2 Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 475.2
• Purity: ~98% (HPLC)
• Form: Supplied as an off-white solid.
• CAS Number: [192703-06-3]