Cdc25 Inhibitor IV, NSC 95397 (2,3-Bis(2-hydroxyethylthio)-1,4-naphthalenedione, PTP Inhibitor XXIX), CAS [[93718-83-3]]

Product Overview

• Article Name: Cdc25 Inhibitor IV, NSC 95397 (2,3-Bis(2-hydroxyethylthio)-1,4-naphthalenedione, PTP Inhibitor XXIX), CAS [[93718-83-3]]
• Biozol Catalog Number: USB-217261
• Supplier Catalog Number: 217261
• Alternative Catalog Number: USB-217261-10
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A cell-permeable, para-naphthoquinone that has been reported to inhibit protein tyrosine phosphatase activity, including Cdc25 dual specificity phosphatase (Ki=32nM, 96nM, and 40nM for Cdc25A, -B, and -C, respectively) and blocks G2M transition in murine carcinoma cells. In addition, it is shown to inhibit S100A4 binding to myosin-IIA via covalent modification of cysteine residues, Cys81 and Cys86, in the target binding cleft (IC50=1.8uM). It demonstrates inhibitory activity against S100A4-mediated depolymerization of myosin-IIA filaments. Synonyms: (2,3-bis-[2-hydroxyethylsulfanyl]-[1,4]naphthoquinone), PTP Inhibitor XXIX CAS Number: 93718-83-3 Molecular Formula: C14H14O4S2 Molecular Weight: 310.4 Solubility: DMSO (100mg/ml, clear red solution) Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 310.4
• Purity: 95% (HPLC)
• Form: Supplied as an orange solid.
• CAS Number: [93718-83-3]