CIQ ((3-Chlorophenyl) [3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]methanone), CAS [[486427-17-2]]

Product Overview

• Article Name: CIQ ((3-Chlorophenyl) [3,4-dihydro-6,7-dimethoxy-1-[(4-methoxyphenoxy)methyl]-2(1H)-isoquinolinyl]methanone), CAS [[486427-17-2]]
• Biozol Catalog Number: USB-217276
• Supplier Catalog Number: 217276
• Alternative Catalog Number: USB-217276-5
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A positive allosteric modulator selective for NR2C/D containingnMDA receptors (EC50 = 2.7 and 2.8uM for NR2C and NR2D, respectively). Increases channel opening frequency of recombinant NR2C/D containingnMDA receptors by two-fold without altering mean open time or EC50 values for glutamate or glycine bindings. No effect on NR2A or NR2B subtypes. CAS Number: 486427-17-2 Formula: C26H26ClNO5 Solubility: DMSO Primary Target: NMDA receptors Molar Mass: 467.94 Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 467.94
• Purity: ~98% (HPLC)
• Form: Supplied as a white powder.
• CAS Number: [486427-17-2]