CPCCOEt ((E)-Ethyl 1,1a,7,7a-tetrahydro-7-(hydroxyimino)cyclopropa[b]chromene-1a-carboxylate, mGlu1 Antagonist, CPCCOEt), CAS [[179067-99-3]]

Product Overview

• Article Name: CPCCOEt ((E)-Ethyl 1,1a,7,7a-tetrahydro-7-(hydroxyimino)cyclopropa[b]chromene-1a-carboxylate, mGlu1 Antagonist, CPCCOEt), CAS [[179067-99-3]]
• Biozol Catalog Number: USB-217283
• Supplier Catalog Number: 217283
• Alternative Catalog Number: USB-217283-5
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A potent, negative allosteric modulator selective for mGlu1 receptors (IC50 = 6.5uM). No effect on other mGlu subtype receptors and ionotropic glutamate receptors at concentrations less than 100uM. Acts by inhibiting an intramolecular interaction between the agonist-bound extracellular domain and the transmembrane domain. Widely used for studies related to peripheral pain and central pain pathways. CAS Number: 179067-99-3 Formula: C13H13NO4 Solubility: DMSO Primary Target: mGlu1 receptors Molar Mass: 247.25 Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 247.25
• Purity: ~98% (HPLC)
• Form: Supplied as a white powder.
• CAS Number: [179067-99-3]