Eliprodil (alpha-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, NMDA Antagonist IX), CAS [[119431-25-3]]

Product Overview

• Article Name: Eliprodil (alpha-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, NMDA Antagonist IX), CAS [[119431-25-3]]
• Biozol Catalog Number: USB-217339
• Supplier Catalog Number: 217339
• Alternative Catalog Number: USB-217339-10
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A negative allosteric modulator selective for NR2B containingnMDA receptors (IC50 = 1, >100, and >100uM for NR2B, NR2A, and NR2C, respectively). Also a potent ligand for alpha1 receptor (Ki = 0.013uM), one of the two types of unique non-opioid, non-phencyclidine brain alpha receptors. Blocks neuronal voltage-gated Ca2+. CAS Number: 119431-25-3 Formula: C20H23ClFNO Solubility: DMSO Primary Target: NMDA receptors Primary Target IC50: 1, > 100, and > 100 M for NR2B, NR2A, and NR2C, respectively. Molar Mass: 347.86 Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 347.86
• Purity: ~99% (HPLC)
• Form: Supplied as a white solid.
• CAS Number: [119431-25-3]