Glucagon-Like Peptide 1 Receptor Agonist, CAS [[281209-71-0]]

Product Overview

• Article Name: Glucagon-Like Peptide 1 Receptor Agonist, CAS [[281209-71-0]]
• Biozol Catalog Number: USB-217385
• Supplier Catalog Number: 217385
• Alternative Catalog Number: USB-217385-5
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A nonpeptidic quinoxaline compound that acts as a GLP-1R agonist and an allosteric modulator of GLP-1 binding. Shown to induce GLP-1R-mediated cAMP production in BHK plasma membrane preparations (EC50=101nM) and potentiate glucose-dependent insulin release in pancreatic islets derived from wild-type, but not GLP-1R -/-, mice. Unlike GLP-1, its biological activity is not inhibited by orthosteric antagonists such as Exendin. Synonyms: 6,7-dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-, 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline (DMB), Compound 2, GLP-1R Agonist CAS Number: 281209-71-0 Molecular Formula: C13H15Cl2N3O2S Molecular Weight: 348.3 Purity: 98% (HPLC) Solubility: DMSO (20mg/ml), Ethanol (10mg/ml) Storage and Stability: Store at 4C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 348.3
• Purity: 98% (HPLC)
• Form: Yellow solid
• CAS Number: [281209-71-0]