GR113808 (5-HT4 Serotonin Receptor Antagonist, GR113808, GR 113808, GR-113808), CAS [[144625-51-4]]

Product Overview

• Article Name: GR113808 (5-HT4 Serotonin Receptor Antagonist, GR113808, GR 113808, GR-113808), CAS [[144625-51-4]]
• Biozol Catalog Number: USB-217398
• Supplier Catalog Number: 217398
• Alternative Catalog Number: USB-217398-10
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A potent and selective antagonist of the serotonin 5-HT4 receptor (pki = 9.3-10.3). GR113808 is commonly used in brain and peripheral in vitro and in vivo in striatum studies (Guinea pig IC50 = 113nM, rat brain membrane Kd = 0.4-1nM) and in cAMP response in CHO and C6 glial cells (EC50 = 79-81nM). Synonyms: 5-HT4 Serotonin Receptor Antagonist, GR113808, GR 113808, GR-113808 CAS No: 144625-51-4 Molecular Formula: C19H27N3O4S Solubility: DMSO or EtOH Primary Target: 5-HT4 Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Purity: 98% (HPLC)
• Form: Supplied as an off-white solid.
• CAS Number: [144625-51-4]