L-701,324 (7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone), CAS [[142326-59-8]]

Product Overview

• Article Name: L-701,324 (7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone), CAS [[142326-59-8]]
• Biozol Catalog Number: USB-217500
• Supplier Catalog Number: 217500
• Alternative Catalog Number: USB-217500-10
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A highly potent and selective antagonist for thenMDA receptor glycine site (IC50 = 2.0nM, Kd = 28nM, ED50 = 0.9nM either intraperitoneal (ip) or oral (po) adminited). The first such compounds with significant activity in the central nervous system following oral dosing and a potent, active anticonvulsant with a reduced propensity to activate mesolimbic dopaminergic systems in rodents. CAS Number: 142326-59-8 Formula: C21H14CINO3 Solubility: DMSO Primary Target: NMDA receptors Primary Target IC50: 2.0nM Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Purity: ~98% (HPLC)
• Form: Supplied as a white powder.
• CAS Number: [142326-59-8]