L-745,870 Trihydrochloride (Dopamine D4 Receptor Antagonist, L-745,870 Trihydrochloride, L-745870, L745870), CAS [[158985-00-3]]

Product Overview

• Article Name: L-745,870 Trihydrochloride (Dopamine D4 Receptor Antagonist, L-745,870 Trihydrochloride, L-745870, L745870), CAS [[158985-00-3]]
• Biozol Catalog Number: USB-217502
• Supplier Catalog Number: 217502
• Alternative Catalog Number: USB-217502-10
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

Selective D4 receptor antagonist with excellent brain penetration. Displays an affinity (Ki) of 0.4nM for human D4 receptors with >1000-fold binding selectivity over D2 and D3 receptors. Does not block agonist-induced activation of GIRK currents. It is used frequently in retinal and CNS studies of D4 modulation. CAS No: 158985-00-3 Molecular Formula: C18H19N4Cl3HCl Solubility: H2O Primary Target: D4 Primary Target Ki: 0.4nM Purity: 99% (HPLC) Form: Supplied as an off-white solid. Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Purity: 99% (HPLC)
• Form: Supplied as an off-white solid.
• CAS Number: [158985-00-3]