LSD1 Inhibitor III, CBB1007 (Histone Lysine Demethylase Inhibitor V, CBB1007, KDM1 Inhibitor III, CBB1007, (Methyl-3-(4-(4-carbamimidoylbenzoyl)piperazine-1-carbonyl)-5-((4-carbamimidoylpiperazin-1-yl)methyl)benzoate, BHC110 Inhib

Product Overview

• Article Name: LSD1 Inhibitor III, CBB1007 (Histone Lysine Demethylase Inhibitor V, CBB1007, KDM1 Inhibitor III, CBB1007, (Methyl-3-(4-(4-carbamimidoylbenzoyl)piperazine-1-carbonyl)-5-((4-carbamimidoylpiperazin-1-yl)methyl)benzoate, BHC110 Inhib
• Biozol Catalog Number: USB-217520
• Supplier Catalog Number: 217520
• Alternative Catalog Number: USB-217520-10
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A cell-permeable amidino-guanidinium compound that acts as a potent, reversible and substrate competitive LSD1 selective inhibitor (IC50=5.27uM for hLSD1) and efficiently blocks LSD1-mediated demethylation of H3K4Me2 and H3K4Me (IC505uM) with no effect on H3K4Me3 and H3K9Me2, and LSD2 and JARID1A activities. Increases H3K4Me2 and H3K4Me contents (IC505uM), and causes activation of epigenetically suppressed CHRM4/M4-ArchR and SCN3A genes in F9 cells (IC503.74uM). Shown to preferentially arrest the growth of pluripotent tumors with minimal effect on non-pluripotent cancer or normal somatic cells (IC50100uM). Synonyms: LSD Inhibitor III, Methyl-3-(4-(4-carbamimidoylbenzoyl)piperazine-1-carbonyl)-5-((4-carbamimidoylpiperazin-1-yl)methyl)benzoate, 3TFA, KDM1 Inhibitor III, Histone Lysine Demethylase Inhibitor V, BHC110 Inhibitor III CAS No: 1379573-92-8 Formula: C27H34N8O4 3CF3CO2H Solubility: DMSO Molecular Weight: 534.6 Storage and Stability: Store at -20C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 534.6
• Purity: 99% (HPLC)
• Form: Supplied as a white solid.
• CAS Number: [1379573-92-8]