MPEP Hydrochloride (6-Methyl-2-(phenylethynyl)pyridine Hydrochloride), CAS [[96206-92-7]]

Catalog Number: USB-217564
Article Name: MPEP Hydrochloride (6-Methyl-2-(phenylethynyl)pyridine Hydrochloride), CAS [[96206-92-7]]
Biozol Catalog Number: USB-217564
Supplier Catalog Number: 217564
Alternative Catalog Number: USB-217564-10
Manufacturer: US Biological
Category: Biochemikalien
A non-competitive, highly potent antagonist selective for mGlu5 receptors (IC50 = 36nM). Also a positive allosteric modulator of mGlu4 and weak anatagonist of nMDA receptors. Biologically active admitted systematically. Widely used in assessing the functional roles of mGlu5 receptors in a variety of research areas, such as learning and memory, sleep, neuroprotection, depression, addiction, anxiety and stress related disorders, analgesia, locomotion, neural plasticity, and Parkinsons disease. CAS Number: 96206-92-7 Formula: C14H11N A HCl Solubility: DMSO Primary Target: mGlu5 receptors Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Purity: ~99% (HPLC)
Form: Supplied as a white solid.
CAS Number: [96206-92-7]