PNU 282987 (PNU-282987, N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide Hydrochloride, alpha7 nAChR Agonist, PNU 282987, alpha 7 Nicotinic Acetylcholine Receptor Agonist, PNU 282987, PNU282987), CAS [[123464-89-1]]

Product Overview

• Article Name: PNU 282987 (PNU-282987, N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide Hydrochloride, alpha7 nAChR Agonist, PNU 282987, alpha 7 Nicotinic Acetylcholine Receptor Agonist, PNU 282987, PNU282987), CAS [[123464-89-1]]
• Biozol Catalog Number: USB-217679
• Supplier Catalog Number: 217679
• Alternative Catalog Number: USB-217679-10
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A potent agonist highly selective for alpha7 nAChRs (Ki = 26nM). Used in investigating the roles of alpha7 nAChRs in sensory gating, learning and memory, cognitive functions, and treatment of Schizophrenia. Synonyms: PNU-282987, N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide hydrochloride, alpha7 nAChR Agonist, PNU 282987, alpha 7 Nicotinic Acetylcholine Receptor Agonist, PNU 282987, PNU282987 CAS No: 123464-89-1 Formula: C14H17ClN2OHCl Solubility: H2O Primary Target: alpha7 nAChRs Primary Target Ki: 26nM Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Purity: 99% (HPLC)
• Form: Supplied as an off-white solid.
• CAS Number: [123464-89-1]