Pre-mRNA Splicing Inhibitor, Isoginkgetin, CAS [[548-19-6]]

Product Overview

• Article Name: Pre-mRNA Splicing Inhibitor, Isoginkgetin, CAS [[548-19-6]]
• Biozol Catalog Number: USB-217696
• Supplier Catalog Number: 217696
• Alternative Catalog Number: USB-217696-10
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A cell-permeable, naturally isolated Ginkgo biloba biflavanoid that acts as a general pre-mRNA splicing inhibitor (ICmax=50uM in splicing assays using HeLa nuclear extract) by blocking the spliceosome-meidated splicing process at the prespliceosome/A complex stage. Isoginkgetin treatment is shown to result in growth arrest in HEK293-derived cultures in a reversible manner without affecting cell viability (33uM for 24h). 217696 is a cell-permeable inhibitor of pre-mRNA splicing. Blocks spliceosome-mediated splicing process at the pre-spliceosome/A complex stage. Synonyms: 8-(5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl)-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one CAS No: 548-19-6 Molecular Formula: C32H22O10 Molecular Weight: 566.5 Solubility: DMSO (100mg/ml) Appearance: Supplied as a yellow solid. Purity: 98% (HPLC) Storage and Stability: Store at -20C under inert atmosphere. Protect from light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 566.5
• Purity: 98% (HPLC)
• Form: Supplied as a yellow solid.
• CAS Number: [548-19-6]