RS 102895 Hydrochloride (1-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4-piperidin]-2(1H)-one Hydrochloride, RS 102895, RS102895), CAS [[300815-41-2]]

Product Overview

• Article Name: RS 102895 Hydrochloride (1-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4-piperidin]-2(1H)-one Hydrochloride, RS 102895, RS102895), CAS [[300815-41-2]]
• Biozol Catalog Number: USB-217756
• Supplier Catalog Number: 217756
• Alternative Catalog Number: USB-217756-5
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A selective antagonist for CCR2 receptors (IC50 = 0.36 and 17.8uM for CCR2b and CCR1 receptors, respectively). Blocks monocyte chemoattractant protein-1 induced calcium influx and chemotaxis (IC50 = 32nM and 1.7uM respectively). A potential anti-inflammatory therapeutic agent by Inhibiting alpha1A, alpha1D and 5-HT1A receptors. Synonyms: 1-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4-piperidin]-2(1H)-one hydrochloride, RS 102895, RS102895 CAS Number: 300815-41-2 Formula: C21H21F3N2O2HCl Solubility: DMSO Appearance: Supplied as an off-white powder. Primary Target: CCR2 Primary Target IC50: 0.36 and 17.8uM for human recombinant CCR2b and CCR1 receptors, respectively. Molecular Weight: 426.86 Storage and Stability: Store at 4C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 426.86
• Purity: 98% (HPLC)
• Form: Supplied as an off-white powder.
• CAS Number: [300815-41-2]