SB 399885 Hydrochloride (5-HT6 Receptor Antagonist, SB 399885), CAS [[402713-80-8]]

Product Overview

• Article Name: SB 399885 Hydrochloride (5-HT6 Receptor Antagonist, SB 399885), CAS [[402713-80-8]]
• Biozol Catalog Number: USB-217780
• Supplier Catalog Number: 217780
• Alternative Catalog Number: USB-217780-10,USB-217780-25,USB-217780-50
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A high affinity 5-HT6 Receptor antagonist (pKi = 9.0). Good solubility (to 100mM in water or DMSO), oral availability, and penetrant to blood brain barrier. Over 200-fold selective for 5-HT6 receptors vs all receptors, ion channels and enzymes tested in Hirst et al. 2006 publication. Shows nootropic, antidepressant and axiolytic effects comparable to well-described drugs such as diazepam, and therefore has been proposed as novel treatment for schizoprenia and Alzheimers disease. Solubility: DMSO or H2O Primary Target: 5-HT6 Primary Target Ki: 1nM Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Purity: ~99% (HPLC)
• Form: Supplied as a white solid.
• CAS Number: [402713-80-8]