TCN-201 (3-Chloro-4-fluoro-N-[(4-{[2-(phenylcarbonyl)hydrazino]carbonyl}phenyl)methyl]benzenesulfonamide, NMDA Antagonist X), CAS [[852918-02-6]]

Product Overview

• Article Name: TCN-201 (3-Chloro-4-fluoro-N-[(4-{[2-(phenylcarbonyl)hydrazino]carbonyl}phenyl)methyl]benzenesulfonamide, NMDA Antagonist X), CAS [[852918-02-6]]
• Biozol Catalog Number: USB-217829
• Supplier Catalog Number: 217829
• Alternative Catalog Number: USB-217829-5
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

A negative allosteric modulator selective for NR2A containingnMDA receptors (pIC50 = 6.8 and <4.3uM for NR2A and NR2B, respectively). No effect on NR2B-containingnMDA receptors with concentrations less than 50 mM. Inhibition on NR2A containingnMDA receptors is glycine (or D-serine)-binding, but not glutamate-binding, dependent. Formula: C21H17ClFN3O4S Solubility: DMSO Primary Target: NMDA receptors Molar Mass: 461.89 Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Product Properties

• Molecular Weight: 461.89
• Purity: ~98% (HPLC)
• Form: Supplied as a white powder.
• CAS Number: [852918-02-6]