VP40 coordinates numerous functions in the viral life cycle of the Ebola virus. These include: regulation of viral transcription, morphogenesis, packaging and budding of mature virions. VP40 goes through intermediate states of assembly (e.g. octamers). It has been noted that proteins encoded by EBOV (VP30, VP35, and VP40) act independently as suppressors of RNA silencing, indicating that the virus actively resists cellular RNAi during replication. Applications: Suitable for use in ELISA, Western Blot and Lateral Flow. Other applications not tested. Recommended Dilution: Western Blot: 1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clonality:
Monoclonal
Clone Designation:
[15B328]
Isotype:
IgG2a
Purity:
Purified by Protein G affinity chromatography.
Form:
Supplied as a liquid in PBS, pH 7.3, 0.09% sodium azide.
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