6-Diazo-5-oxo-L-norleucine, CAS [[157-03-9]]

Product Overview

• Article Name: 6-Diazo-5-oxo-L-norleucine, CAS [[157-03-9]]
• Biozol Catalog Number: USB-234678
• Supplier Catalog Number: 234678
• Alternative Catalog Number: USB-234678-5,USB-234678-10,USB-234678-25,USB-234678-50
• Manufacturer: US Biological
• Category: Biochemikalien

Product Description

6-Diazo-5-oxo-L-nor-Leucine (DON) is a glutamine analog that inhibits glutaminases (Ki = 6 µM) and other glutamine-utilizing enzymes, including cytidine triphosphate synthase (CTPS), which uses glutamine in the synthesis of CTP.1,2,3 DON is commonly used in cells or tissues but its use in whole animals is limited by its teratogenicity.3,4,5 Synonyms: DON, NSC 7365 CAS No: 157-03-9 Molecular Formula: C6H9N3O3 Molecular Weight: 171.15 Appearance: White to off-white powder Purity: 95% Melting Point: 129-131C Solubility: DMSO (Slightly, Heated, Sonicated), Water (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Properties

• Molecular Weight: 171.15
• Purity: 95%
• Form: White to off-white powder
• CAS Number: [157-03-9]