Amikacin disulfate salt is a potent aminoglycoside antibiotic, primarily utilized in the treatment of severe bacterial infections, particularly those caused by Gram-negative bacteria. This compound is especially valuable in clinical settings for its effectiveness against multi-drug resistant strains, making it a critical option for healthcare professionals. Its unique structure enhances its stability and efficacy, allowing for targeted action against pathogens while minimizing toxicity to human cells. Synonyms: Amikacin disulfate salt, (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide disulfate, O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(16)O-[6-amino-6-deoxy-alpha-D-glucopyranosyl-(14)]-N1-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-D-streptamine Sulfate, Antibiotic BB-K8 sulfate Antibiotic Activity Spectrum: Gram-negative bacteria mycobacteria CAS No: 39831-55-5 Molecular Formula: C22H43N5O132H2SO4 Molecular Weight: 781.76 Purity (Potency): 674-786ug/mg (Assay on anhydrous basis) Appearance: White crystalline powder Melting Point: 220-230C (dec.) Optical Rotation: [a]D20 = +76 to 84 pH: 2-4 Loss on Drying: 13% Residue on Ignition: 1% Identification: Test for A: Infrared spectrum : Conforms to standard Test for B: To pass test Test for C: It gives reaction of sulfates Solubility: Water: ~50mg/ml, Acetone, DMSO: Insoluble Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at 4C. Hygroscopic, Heat Sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight:
781.76
CAS Number:
[39831-55-5]
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